• Aileen Kharat, Marie Simon, and Claude Guérin.
• Service de Pneumologie, Hôpitaux Universitaires de Genève.
• Curr Opin Crit Care. 2022 Feb 1; 28 (1): 576557-65.

Purpose Of ReviewProne position has been widely used in the COVID-19 pandemic, with an extension of its use in patients with spontaneous breathing ('awake prone'). We herein propose a review of the current literature on prone position in mechanical ventilation and while spontaneous breathing in patients with COVID-19 pneumonia or COVID-19 ARDS.Recent FindingsA literature search retrieved 70 studies separating whether patient was intubated (24 studies) or nonintubated (46 studies). The outcomes analyzed were intubation rate, mortality and respiratory response to prone. In nonintubated patient receiving prone position, the main finding was mortality reduction in ICU and outside ICU setting.SummaryThe final results of the several randomized control trials completed or ongoing are needed to confirm the trend of these results. In intubated patients, observational studies showed that responders to prone in terms of oxygenation had a better survival than nonresponders.Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

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