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Eur. J. Intern. Med. · Dec 2021
Meta AnalysisHydroxichloroquine for COVID-19 infection: Do we have a final word after one year?
- Augusto Di Castelnuovo, Simona Costanzo, Alessandro Gialluisi, Licia Iacoviello, and Giovanni de Gaetano.
- Mediterranea Cardiocentro, Napoli, Italy. Electronic address: dicastel@ngi.it.
- Eur. J. Intern. Med. 2021 Dec 1; 94: 4-5.
AbstractThe results presently available from randomised clinical trials and their meta-analysis indicate that Hydroxychloroquine is not associated in COVID-19 patients with either decreased mortality or clinical worsening. Thus, the use of Hydroxychloroquine in COVID-19 patients cannot at present be encouraged. However, the hypothesis that Hydroxychloroquine might have a beneficial role in subgroups of patients at low risk and/or when used at low dosage (≤ 400 mg/day) deserves to be tested in large, well designed randomised clinical trials.Copyright © 2021 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
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