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Best Pract Res Clin Rheumatol · Feb 2016
ReviewConnective tissue disease-related interstitial lung disease.
- M Kristen Demoruelle, Shikha Mittoo, and Joshua J Solomon.
- University of Colorado Denver, Division of Rheumatology, Aurora, CO, USA.
- Best Pract Res Clin Rheumatol. 2016 Feb 1; 30 (1): 39-52.
AbstractInterstitial lung disease (ILD) is commonly present in patients with an underlying connective tissue disease (CTD), particularly those with systemic sclerosis, rheumatoid arthritis, and inflammatory myositis. The clinical spectrum can range from asymptomatic findings on imaging to respiratory failure and death. Distinguishing features in the clinical, radiographic, and histopathologic characteristics of CTD-ILD subsets can predict prognosis and treatment response. Treatment often consists of combinations of immunosuppressive medications, but there is a paucity of guidance in the literature to help clinicians determine appropriate screening and management of CTD-ILD. As such, there is a critical need for studies that can elucidate the natural history of the CTD-ILD, as well as clarify optimal therapies for CTD patients with ILD.Copyright © 2016 Elsevier Ltd. All rights reserved.
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