• Bryan Leal, Héctor Torres, Ángela Roco, Ricardo Román, Mario Rojo, Elena Nieto, and Luis Quiñones.
• Servicio de Salud Metropolitano Occidente, Hospital Metropolitano, Santiago, Chile.
• Rev Med Chil. 2021 May 1; 149 (5): 724-732.

BackgroundVitamin K antagonists such as acenocoumarol and warfarin are usually indicated for the treatment of Atrial Fibrillation (AF). The Therapeutic Range Time (TRT) is a quality of treatment indicator. Values greater than 65% are associated with significantly lower stroke and bleeding rates. Proper pharmaceutical care improves TRT.AimTo evaluate the impact of pharmaceutical care in patients with AF treated with acenocoumarol.Material And MethodsWe studied 41 patients using acenocoumarol for AF aged 71 ± 11 years (43% women). They received pharmaceutical counseling during 12 weeks. TRT was calculated retrospectively for the year before counseling and prospectively during the intervention period.ResultsAfter receiving pharmaceutical counseling TRT improved from 29% at baseline to 46% at the end of the intervention (p < 0.01). After pharmaceutical care, the adherence of patients to drug treatment improved from 27% at baseline to 85% at the end of the study. The user satisfaction survey of the pharmaceutical care received showed a high degree of patient satisfaction.ConclusionsPharmaceutical care in patients with oral anticoagulant treatment improves TRT of anticoagulation. It is accepted and positively evaluated by patients.

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