• Psychiatr. Clin. North Am. · Jun 2013

    Review

    Toxic leukoencephalopathies.

    • Laura M Tormoehlen.
    • Department of Neurology, Indiana University School of Medicine, 545 Barnhill Drive, Indianapolis, IN 46202, USA. laumjone@iupui.edu
    • Psychiatr. Clin. North Am. 2013 Jun 1; 36 (2): 277-92.

    AbstractLeukoencephalopathy is a syndrome of neurologic deficits, including alteration of mental status, caused by pathologic changes in the cerebral white matter. The term, toxic leukoencephalopathy, encompasses a wide variety of exposures and clinical presentations. The diagnosis in these Frontiers in Clinical Neurotoxicology syndromes is made by careful attention to the history, clinical features, and radiologic findings. This article details three of the best-defined toxic leukoencephalopathies: delayed posthypoxic leukoencephalopathy, including delayed neurologic sequelae after carbon monoxide poisoning; heroin inhalation leukoencephalopathy; and posterior reversible encephalopathy syndrome.Copyright © 2013 Elsevier Inc. All rights reserved.

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