• Vet. Clin. North Am. Equine Pract. · Apr 2011

    Review

    Water homeostasis and diabetes insipidus in horses.

    • Harold C Schott.
    • Department of Large Animal Clinical Sciences, College of Veterinary Medicine, D-202 Veterinary Medical Center, Michigan State University, East Lansing, MI 48824-1314, USA. schott@cvm.msu.edu
    • Vet. Clin. North Am. Equine Pract. 2011 Apr 1; 27 (1): 175-95.

    AbstractDiabetes insipidus (DI) is a rare disorder of horses characterized by profound polyuria and polydipsia (PU/PD), which can be caused by loss of production of arginine vasopressin (AVP). This condition is termed neurogenic or central DI. DI may also develop with absence or loss of AVP receptors or activity on the basolateral membrane of collecting-duct epithelial cells. This condition is termed nephrogenic DI. Equine clinicians may differentiate true DI from more common causes of PU/PD by a systematic diagnostic approach. DI may not be a correctable disorder, and supportive care of affected horses requires an adequate water source.Copyright © 2011 Elsevier Inc. All rights reserved.

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