• Am. J. Epidemiol. · Sep 2007

    Comment

    Invited commentary: Fewell and colleagues--fuel for debate.

    • James Marshall.
    • Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, NY 14263, USA. james.marshall@roswellpark.org
    • Am. J. Epidemiol. 2007 Sep 15; 166 (6): 656-8; discussion 659-61.

    AbstractConcern over the impact of flawed measurement continues to nag epidemiology. Early studies indicated that the impact of measurement error is benign, leading generally only to attenuation of associations; more recent research has documented that this impact, especially within the setting of multivariate modeling, cannot be expected always to be benign. It can, for example, be a source of unsettling inconsistency. Fewell and colleagues (Am J Epidemiol 2007;166:646-655) show that residual confounding is especially persistent in the presence of multivariate confounding.

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