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Respiratory investigation · May 2014
Case ReportsThree cases of mesalazine-induced pneumonitis with eosinophilia.
- Miyo Inoue, Nobuyuki Horita, Naoko Kimura, Ryota Kojima, and Naoki Miyazawa.
- Department of Respiratory Medicine, Saiseikai Yokohamashi Nanbu Hospital, 3-2-10, Kounandai, Kounan-ku, Yokohama 234-8503, Japan. Electronic address: miyon0312@hotmail.com.
- Respir Investig. 2014 May 1; 52 (3): 209-12.
AbstractOral mesalazine, or 5-aminosalicylate, is one of the first-choice medications for the treatment of ulcerative colitis and is commonly used for both induction and maintenance therapy. In a 6-month period, we treated three cases of mesalazine-induced pneumonitis. In all three cases, computed tomography images revealed upper lobe dominant bilateral peripherally localized consolidations. Such images are commonly observed in patients with cryptogenic organizing pneumonia or chronic eosinophilic pneumonia. Computed tomography images for mesalazine-induced pneumonitis have been rarely reported in the literature. Copyright © 2014 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.
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