• Nature medicine · Nov 2020

    Seasonal coronavirus protective immunity is short-lasting.

    • Arthur W D Edridge, Joanna Kaczorowska, Alexis C R Hoste, Margreet Bakker, Michelle Klein, Katherine Loens, Maarten F Jebbink, Amy Matser, Cormac M Kinsella, Paloma Rueda, Margareta Ieven, Herman Goossens, Maria Prins, Patricia Sastre, Martin Deijs, and Lia van der Hoek.
    • Laboratory of Experimental Virology, Department of Medical Microbiology and Infection Prevention, Amsterdam Infection & Immunity Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
    • Nat. Med. 2020 Nov 1; 26 (11): 1691-1693.

    AbstractA key unsolved question in the current coronavirus disease 2019 (COVID-19) pandemic is the duration of acquired immunity. Insights from infections with the four seasonal human coronaviruses might reveal common characteristics applicable to all human coronaviruses. We monitored healthy individuals for more than 35 years and determined that reinfection with the same seasonal coronavirus occurred frequently at 12 months after infection.

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