• Oncology · Jan 1980

    Hypothalamo-pituitary-adrenal axis in patients with prostatic carcinoma.

    • S Madajewicz, A Bhargava, Z Wajsman, A Mittelman, J Fitzpatrick, and G P Murphy.
    • Oncology. 1980 Jan 1; 37 (6): 373-5.

    AbstractInsulin-induced pituitary growth hormone (GH), adrenocorticotrophic hormone (ACTH) and adrenal cortical response were studied in 12 patients with prostatic carcinoma. 3 patients demonstrated significant abnormal GH release associated with concentrations which remained on a high plateau during the study. 5 patients showed lack of ACTH-cortisol response to insulin-induced hypoglycemia. Those patients subsequently presented clinically with rapidly progressing disease.

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