• Di Yi Jun Yi Da Xue Xue Bao · Sep 2003

    [Determination of serum superoxide dismutase, glutathione peroxidase, total antioxidative capacity, malondialdehyde in patients with pneumonia].

    • Guo-fu Li, Yi-fan He, Mu-rong Huang, Jie-lian Guo, Qing-tan Wu, and Shun-jin Chen.
    • Clinical Laboratory, Zhanjiang Central People's Hospital, Zhanjiang 524037, China.
    • Di Yi Jun Yi Da Xue Xue Bao. 2003 Sep 1; 23 (9): 961-2.

    ObjectiveTo determine the levels of serum superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), total antioxidative capacity (T-AOC) and malondialdehyde (MDA) in patients with pneumonia.MethodsSixty-eight patients with pneumonia were divided into group of acute pneumonia, group of chronic bronchitis complicated by lung infection, and group of bronchopneumonia. The levels of serum SOD, GSH-Px, T-AOC and MDA were detected by colorimetry in the 68 patients and 76 normal control subjects.ResultsThe serum levels of SOD, GSH-Px and MDA were all significantly higher, while T-AOC significantly lower in the 3 patient groups than in the normal subjects. Significant difference in the measurements was also noted between the 3 groups (P < 0.01).ConclusionThe determination of serum SOD, GSH-Px, T-AOC and MDA may be helpful for the diagnosis and treatment of pneumonia.

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