• W V Med J · Jul 2004

    Case Reports

    Methadone-induced torsade de pointes in a patient with normal baseline QT interval.

    • Ammar Almehmi, Amer M Malas, Mohammed Yousufuddin, and J Gregory Rosencrance.
    • Dept. of Medicine, West Virginia University School of Medicine, Charleston Division, USA.
    • W V Med J. 2004 Jul 1; 100 (4): 147-8.

    AbstractTorsade de pointes (TdP) is a life threatening cardiac arrhythmia that is typically associated with prolongation of the QT interval. A wide variety of nonantiarrthymic medications may trigger TdP in patients with prolonged QT interval, only a few reports have described an association between TdP and methadone. We report a case of TdP caused by a large dose of methadone in a patient with presumably normal QT interval at baseline prior to his presentation at the hospital.

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