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- Takuya Suda, Takeshi Zoshima, Kiyoaki Ito, Ichiro Mizushima, and Mitsuhiro Kawano.
- Department of Rheumatology, Kanazawa University Graduate School of Medicine, Japan.
- Intern. Med. 2022 Jun 1; 61 (11): 1767-1774.
AbstractThe efficacy of early immunosuppressive therapy without invasive therapy, such as endovascular or surgical revascularization, for pulmonary hypertension due to Takayasu arteritis (TAK-PH) remains to be elucidated. We herein report two cases of TAK-PH due to pulmonary arteritis successfully treated with early immunosuppressive therapy. A literature review of 42 cases of TAK-PH with pulmonary artery involvement showed that the cases treated with immunosuppressive therapy early after the onset (within 12 months) had a higher erythrocyte sedimentation rate and better outcome without invasive therapy than those treated later. TAK-PH may be successfully treated with immunosuppressive therapy without invasive therapy when diagnosed early with high disease activity.
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