• American heart journal · Jan 2019

    Randomized Controlled Trial Multicenter Study Pragmatic Clinical Trial

    An international cluster-randomized quality improvement trial to increase the adherence to evidence-based therapies for acute ischemic stroke and transient ischemic attack patients: Rationale and design of the BRIDGE STROKE Trial.

    • Maria Julia Machline-Carrion, Eliana Vieira Santucci, Lucas Petri Damiani, Cecilia Bahit, Germán Málaga, Octávio Marques Pontes-Neto, MartinsSheila Cristina OuriquesSCOHospital das Clínicas de Porto Alegre, Porto Alegre, RS, Brazil., Viviane Flumignan Zétola, Karina Normilio-Silva, de FreitasGabriel RodriguesGRInstituto D'Or de Ensino e Pesquisa, Rio de Janeiro, RJ, Brazil., Alessandra Gorgulho, Antônio De Salles, da SilvaBeatriz Gonzales PachecoBGPResearch Institute HCor-Hospital do Coração, São Paulo, SP, Brazil., Juliana Yamashita Santos, de Andrade JesuínoIsabellaIResearch Institute HCor-Hospital do Coração, São Paulo, SP, Brazil., Priscila Regina Torres Bueno, Alexandre Biasi Cavalcanti, Hélio Penna Guimarães, Ying Xian, Janet Prvu Bettger, Renato D Lopes, Eric D Peterson, and Otávio Berwanger.
    • Research Institute HCor-Hospital do Coração, São Paulo, SP, Brazil. Electronic address: mjuliacarrion@gmail.com.
    • Am. Heart J. 2019 Jan 1; 207: 49-57.

    BackgroundTranslating evidence into clinical practice in the management of acute ischemic stroke (AIS) and transient ischemic attack (TIA) is challenging especially in low- and middle-income countries.ObjectivesThe aim of this study is to assess the effect of a multifaceted quality improvement intervention on adherence to evidence-based therapies for AIS and TIA patients care.DesignWe designed a pragmatic, 2-arm cluster-randomized trial involving 36 clusters and 1624 patients from Brazil, Argentina, and Peru. Hospitals are randomized to receive a multifaceted quality improvement intervention (intervention group) or to routine care (control group). The BRIDGE Stroke multifaceted quality improvement intervention includes case management, reminders, health care providers' educational materials (including treatment algorithms), interactive workshops, and audit and feedback reports. Primary outcome is a composite adherence score to AIS and TIA performance measures. Secondary outcomes include an "all or none" composite end point to performance measures, the individual components of the composite end points, and clinical outcomes at 90 days following admission (stroke recurrence, death, and disability measured by the modified Rankin scale).SummaryThe BRIDGE Stroke Trial is an international pragmatic evaluation of a multifaceted quality improvement intervention. If effective, this intervention could be potentially extended widely to improve the quality of care and outcomes of patients with AIS or TIA.Copyright © 2018 Elsevier Inc. All rights reserved.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…