• Arch. Esp. Urol. · Mar 2007

    [En bloc transplantation of pediatric donor kidneys to adult receptors].

    • José Emilio Hernández Sánchez, Angel Gómez Vegas, Jesús Blázquez Izquierdo, Juan Grimalt Alvarez, María Jesús Pérez Contín, Manuel Rabadán Marina, Luis San José Manso, Miguel Alonso Prieto, Natalia Pérez Romero, and Angel Silmi Moyano.
    • Servicios de Urología y Cirugia General, Hospital Clinico San Carlos, Madrid, España. dr_emilio_hernandez@hotmail.com
    • Arch. Esp. Urol. 2007 Mar 1; 60 (2): 137-46.

    ObjectivesAnalysis of all pediatric donor en bloc transplants to adult receptors performed in our department.MethodsRetrospective analysis of 73 en bloc kidney transplants and 497 adult transplants performed in our centre from 1990 to 2004. Mean follow-up was 50.23 months (10.18-89.05 months). All patients received the same immunosuppression, although it evolved with time.ResultsThere were significant differences in terms of nonfunctioning kidneys and delayed graft function, more frequent in pediatric en bloc and adult transplants, respectively. Pediatric kidneys provided better renal function and less proteinuria. Patient and graft survivals were similar in both groups. One and five-year graft survivals were 83.56% and 8 1.47% for pediatric donor kidneys, and 91.50% and 86.99% for adult donor kidneys. Vascular complications were the most frequent cause of graft loss for the en bloc transplants.ConclusionsPediatric donor en bloc transplants have an excellent survival and function in the middle and long-term. Vascular complications are the main cause of pediatric donor graft loss. The adoption of a pediatric donor en bloc transplant program increases the transplant activity.

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