• Br J Anaesth · Feb 2022

    Editorial Comment

    Massive transfusion and severe blood shortages: establishing and implementing predictors of futility.

    • Domagoj Mladinov and Steven M Frank.
    • Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address: dmladinov@uabmc.edu.
    • Br J Anaesth. 2022 Feb 1; 128 (2): e71-e74.

    AbstractMassive transfusion protocols were developed to deliver blood for life-threatening haemorrhage; however, there are no guidelines to advise when massive transfusion protocols may be considered futile. Early recognition of clinical futility remains a challenge as studies have not identified variables that can accurately determine early mortality. As blood is a scarce resource, efforts to distribute it equitably to all patients who would benefit are of paramount importance. In this editorial we discuss recent data and various aspects important in developing and implementing tools that assist with determining futility in massive transfusion.Copyright © 2021 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.

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