• Elias Tzelepis, Christos F Kampolis, Ioanna Vlachadami, Maria Moschovi, Maria Alamani, and Gregory Kaltsas.
• Department of Pathophysiology, 'Laiko' Hospital, University of Athens Medical School, Athens, Greece.
• Clin Respir J. 2016 Mar 1; 10 (2): 250-4.

Background And AimsSweet's syndrome or acute febrile neutrophilic dermatosis is characterized by fever, leukocytosis and tender erythematous plaques, which show infiltration by mature neutrophils on histological examination. Pulmonary involvement is rare in Sweet's syndrome.MethodWe describe the case of a 17-year-old man with a myelodysplastic syndrome following therapy for Hodgkin's lymphoma who developed Sweet's syndrome and cryptogenic organizing pneumonia. In addition, we conducted a review of the related English literature.ResultsLiterature review yielded six similar reports of biopsy-proven cryptogenic organizing pneumonia associated with Sweet's syndrome. We present the clinical and laboratory characteristics, as well as the response to treatment, of all cases of cryptogenic organizing pneumonia reported in patients with Sweet's syndrome.ConclusionsCryptogenic organizing pneumonia is a rare manifestation of Sweet's syndrome, which may be complicated by respiratory failure. Prompt treatment with corticosteroids usually leads to clinical and radiographic improvement.© 2014 John Wiley & Sons Ltd.

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