• Onofre Moran-Mendoza, Sharina Aldhaheri, Connor J A Black, Marie Clements-Baker, Mohamed Khalil, and Alexander Boag.
• Queen's University, Kingston, ON, Canada; Kingston Health Sciences Center, Kingston, ON, Canada. Electronic address: morano@queensu.ca.
• Chest. 2021 Sep 1; 160 (3): e259-e263.

AbstractHypersensitivity pneumonitis (HP) is an inflammatory and/or fibrotic disease affecting the lung parenchyma and small airways. It typically results from an immune-mediated reaction provoked by an overt or occult inhaled antigen in susceptible individuals. The chronic or fibrotic form of HP has a poor prognosis, especially when no inciting antigen is identified, which occurs in up to 60% of cases. We report two cases of HP associated with exposure to mold in foam pillows and a mattress, which has not previously been reported as a risk factor for HP. Given the high prevalence of foam in pillows and mattresses, mold in foam in bedding may explain many HP cases with a previously unrecognized cause. Early identification and avoidance of foam in bedding may prevent HP progression to end-stage pulmonary fibrosis and death.Copyright © 2021 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

3 keywords...

hide…