• Rev Assoc Med Bras (1992) · Sep 2021

    Height adjustment reduces occurrence of low bone mineral density in children and adolescents with HIV.

    • Leonardo Bandeira de Andrade, Thiago Fachini Nogueira, and Deisi Maria Vargas.
    • Universidade de Blumenau, Centro de Ciências de Saúde, Departamento de Medicina - Blumenau (SC), Brazil.
    • Rev Assoc Med Bras (1992). 2021 Sep 1; 67 (9): 1240-1245.

    ObjectiveThe aim of this study was to quantify the reduction of bone mineral density with and without height adjustment.MethodsA cross-sectional study was performed with 69 Brazilian children and adolescents vertically infected by HIV. Bone mineral density was measured by dual-energy absorptiometry in the lumbar spine. Anthropometric, demographic, and clinical variables were analyzed. A specific calculator was used for height adjustment.ResultsThe majority of participants (52.2%) were adolescents and did not present with immunological alterations (61%). Reduced bone mineral density (Z-score <-1) was present in 23.2% and low bone mass (Z-score <-2) in 5.8%. After height adjustment, these occurrences decreased to 11.6% and 0%, respectively. Patients with reduced bone mineral density had a higher mean age and lower body mass index than patients with normal bone mineral density.ConclusionThe occurrence of reduced bone mineral density decreased after adjustment for height.

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