• Jang-Hoon Oh, Hyug-Gi Kim, Kyung Mi Lee, Chang-Woo Ryu, Soonchan Park, Ji Hye Jang, Hyun Seok Choi, and Eui Jong Kim.
• Department of Biomedical Science and Technology, Graduate School, Kyung Hee University, Seoul, Korea.
• Yonsei Med. J. 2021 Dec 1; 62 (12): 112511351125-1135.

PurposeThis study aimed to propose an effective end-to-end process in medical imaging using an independent task learning (ITL) algorithm and to evaluate its performance in maxillary sinusitis applications.Materials And MethodsFor the internal dataset, 2122 Waters' view X-ray images, which included 1376 normal and 746 sinusitis images, were divided into training (n=1824) and test (n=298) datasets. For external validation, 700 images, including 379 normal and 321 sinusitis images, from three different institutions were evaluated. To develop the automatic diagnosis system algorithm, four processing steps were performed: 1) preprocessing for ITL, 2) facial patch detection, 3) maxillary sinusitis detection, and 4) a localization report with the sinusitis detector.ResultsThe accuracy of facial patch detection, which was the first step in the end-to-end algorithm, was 100%, 100%, 99.5%, and 97.5% for the internal set and external validation sets #1, #2, and #3, respectively. The accuracy and area under the receiver operating characteristic curve (AUC) of maxillary sinusitis detection were 88.93% (0.89), 91.67% (0.90), 90.45% (0.86), and 85.13% (0.85) for the internal set and external validation sets #1, #2, and #3, respectively. The accuracy and AUC of the fully automatic sinusitis diagnosis system, including site localization, were 79.87% (0.80), 84.67% (0.82), 83.92% (0.82), and 73.85% (0.74) for the internal set and external validation sets #1, #2, and #3, respectively.ConclusionITL application for maxillary sinusitis showed reasonable performance in internal and external validation tests, compared with applications used in previous studies.© Copyright: Yonsei University College of Medicine 2021.

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