• L I Garegnani, P Rosón Rodriguez, J V A Franco, and C Escobar Liquitay.
• Instituto Universitario Hospital Italiano, Ciudad Autónoma de Buenos Aires, Argentina. Electronic address: luisgaregnani@gmail.com.
• Med Intensiva (Engl Ed). 2021 Oct 1; 45 (7): 387-394.

ObjectiveTo evaluate the effects of esophageal pressure monitoring in adult patients with mechanical ventilation requirements in the Intensive Care Unit.DesignA systematic review (PROSPERO Register CRD42018118583) was carried out.SettingIntensive therapy. Critical care.Patients Or ParticipantsAdults with mechanical ventilation requirement in the Intensive Care Unit.InterventionsEsophageal pressure monitoring.Outcomes Of InterestIntensive Care Unit mortality and length of stay, mechanical ventilation days, adverse events.ResultsFour studies with 301 participants were included. Esophageal pressure monitoring during mechanical ventilation had little or no effect on mortality in intensive care at 28 days (RR 0.74; 95% CI 0.31-1.76; participants 261; studies 2; I2: 68%), with little or no differences in ICU length of stay (MD 0.48; 95% CI -1.90 to 2.85; participants 284; studies 3; I2: 7%) or impact upon adverse events (RR 0.74; 95% CI 0.50-1.09; participants 261; studies 2; I2: 0%). There is uncertainty about whether esophageal pressure monitoring reduces the duration of mechanical ventilation.ConclusionsEvidence of low or very low certainty indicates that esophageal pressure monitoring during mechanical ventilation would produce little or no effect on Intensive Care Unit mortality, Intensive Care Unit length of stay, days on mechanical ventilation or adverse events.Copyright © 2020 Elsevier España, S.L.U. and SEMICYUC. All rights reserved.

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