• Internal medicine · Jun 2022

    Case Reports

    IgG4-Related Hypertrophic Pachymeningitis with Skull Base Involvement Presenting with Isolated Glossopharyngeal and Vagus Nerve Palsy: A Case Report.

    • Risa Suzuki, Reiji Koide, Shuya Hirano, Takafumi Mashiko, Tadashi Ozawa, Kumiko Miura, Kosuke Matsuzono, Saeko Uemura, Ryota Tanaka, Harushi Mori, and Shigeru Fujimoto.
    • Division of Neurology, Department of Medicine, Jichi Medical University School of Medicine, Japan.
    • Intern. Med. 2022 Jun 1; 61 (11): 1753-1755.

    AbstractWe herein report a 70-year-old man diagnosed with IgG4-related hypertrophic pachymeningitis with skull base involvement, who presented with isolated glossopharyngeal and vagus nerve palsy. Contrast-enhanced magnetic resonance imaging (MRI) showed enhanced dural thickening of the posterior clivus and skull base involvement. When a patient with hypertrophic pachymeningitis presents with isolated cranial neuropathy without systemic manifestations or definite MRI abnormalities, it is difficult to make a diagnosis, and the patient may be misdiagnosed. This case suggests that a detailed radiological evaluation including contrast enhancement of the skull base is very important in patients with isolated glossopharyngeal and vagus nerve palsy.

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