• A&A practice · Nov 2021

    Case Reports

    Malignant Hyperthermia During Cardiac Surgery Successfully Treated by Deep Hypothermia Using Cardiopulmonary Bypass: A Case Report.

    • Luuk R van den Bersselaar, Markus W Hollmann, Jeanette M M H van den Goor, Jacobus A Winkelman, SnoeckMarc M JMMJFrom the Malignant Hyperthermia Investigation Unit, Department of Anaesthesiology, Canisius Wilhelmina Hospital, Nijmegen, the Netherlands., and Oskar T Corsmit.
    • From the Malignant Hyperthermia Investigation Unit, Department of Anaesthesiology, Canisius Wilhelmina Hospital, Nijmegen, the Netherlands.
    • A A Pract. 2021 Nov 17; 15 (11): e01546.

    AbstractMalignant hyperthermia (MH) is a life-threatening hypermetabolic disorder triggered by volatile anesthetics and/or succinylcholine. We report a case of a 58-year-old patient with a type-A aortic dissection. After induction of general anesthesia, a hypermetabolic reaction was successfully treated by deep hypothermia using cardiopulmonary bypass. Dantrolene became available in theater after the hypermetabolism was already treated successfully by hypothermia. Because of a low suspicion of MH, dantrolene was not administered when it became available. The patient fully recovered, and MH susceptibility was confirmed. Cardiopulmonary bypass should be considered to treat MH in case dantrolene and conservative therapy are unavailable or insufficient.Copyright © 2021 International Anesthesia Research Society.

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