• Ida K Haugen, Iris Eshed, Frederique Gandjbakhch, Violaine Foltz, Mikkel Østergaard, Pernille Bøyesen, Paul Bird, Harry K Genant, Charles G Peterfy, and Philip G Conaghan.
• From the Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Diagnostic Imaging, Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel; Department of Rheumatology, Pitié Salpêtriere Hospital, APHP, Université Pierre et Marie Curie, Paris, France; Copenhagen Center for Arthritis Research, Center for Rheumatology and Spinal Diseases, Glostrup Hospital, Glostrup, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Department of Rheumatology, St. George Hospital, Sydney, Australia; St. George Clinical School, University of New South Wales, Sydney, Australia; Departments of Radiology and Medicine, University of California San Francisco, San Francisco, California, USA; Synarc Inc., Newark, California, USA; Spire Sciences Inc., Boca Raton, Florida, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK.I.K. Haugen, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital; I. Eshed, MD, Professor of Radiology, Sheba Medical Center, Tel Aviv University; F. Gandjbakhch, MD, Practicing Rheumatologist, Department of Rheumatology, Pitié Salpêtriere Hospital, APHP, Université Pierre et Marie Curie; V. Foltz, MD, Practicing Rheumatologist, Department of Rheumatology, Pitié Salpêtriere Hospital, APHP, Université Pierre et Marie Curie; M. Østergaard, MD, PhD, DMSc, Professor of Rheumatology, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spinal Diseases, Glostrup Hospital, and Department of Clinical Medicine, University of Copenhagen; P. Bøyesen, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital; P. Bird, BMed (Hons), FRACP, PhD, Practicing Rheumatologist, Department of Rheumatology, St. George Hospital and Senior Lecturer, University of New South Wales; H.K. Genant, MD, FACR, FRC
• J Rheumatol. 2015 Dec 1; 42 (12): 2486-91.

ObjectiveTo evaluate the interreader reliability of change scores and the responsiveness of the OMERACT Hand Osteoarthritis (OA) Magnetic Resonance Image (MRI) Scoring System (HOAMRIS).MethodsPaired MRI (baseline and 5-yr followup) from 20 patients with hand OA were scored with known time sequence by 3 readers according to the HOAMRIS: Synovitis, erosive damage, cysts, osteophytes, cartilage space loss, malalignment, and bone marrow lesions (BML; 0-3 scales with 0.5 increments for synovitis, erosive damage, and BML). Interreader reliability for status and change scores were assessed by intraclass correlation coefficients (ICC), percentage exact agreement and percentage close agreement (PEA/PCA), and smallest detectable change (SDC). Responsiveness was assessed by standardized response means (SRM).ResultsCross-sectional interreader ICC were good to very good (≥ 0.74) for all features except synovitis, cysts, and malalignment (ICC 0.50-0.58). The range of change values was small, leading to low ICC for change scores. The SDC values for sum scores (total range 0-24) varied between 1.97-3.05 (except 1.08 for malalignment). For status scores, PEA/PCA on scores in individual joints across the readers were 8.1-50.0 and 43.8-78.1, respectively. Similarly, PEA/PCA for change scores were 20.6-63.8 and 66.3-93.1, respectively. All features except cysts and BML demonstrated good responsiveness with higher SRM for sum scores (range 0.46-1.62) than for scores in individual joints (range 0.24-0.73).ConclusionGood to very good interreader ICC values were found for cross-sectional readings, whereas the longitudinal reliability was lower because of a smaller range of change scores. All features, except cysts and BML, showed good responsiveness.

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