• Dtsch. Med. Wochenschr. · Nov 2021

    [Pheochromocytoma - Disease Model for Personalized Medicine].

    • Hanna Remde and Svenja Nölting.
    • Medizinische Klinik und Poliklinik I, Lehrstuhl Endokrinologie & Diabetologie, Universitätsklinikum Würzburg, Universität Würzburg.
    • Dtsch. Med. Wochenschr. 2021 Nov 1; 146 (23): 1520-1526.

    AbstractPheochromocytomas and paragangliomas (PPGL) can be related to a uniquely high rate of underlying germline and somatic mutations. Accordingly, they can be assigned into genetic clusters, which are related to a specific biochemical and clinical phenotype as well as a different long term prognosis. The present article discussed how emerging knowledge on the respective clusters allows individual patient management before, during and after occurrence of a PPGL to improve clinical outcome.Thieme. All rights reserved.

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