• Internal medicine · Feb 2022

    MPO-ANCA-positive Microscopic Polyangiitis Following COVID-19 Infection.

    • Soko Kawashima, Mitsumasa Kishimoto, Tomoya Hibino, Hearyoung Lee, Yuriko Sato, Yoshinori Komagata, and Shinya Kaname.
    • Department of Nephrology and Rheumatology, Kyorin University School of Medicine, Japan.
    • Intern. Med. 2022 Feb 15; 61 (4): 567-570.

    AbstractAntineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a systemic disease that causes vasculitis in various organs. Although the cause of the onset is unknown, infection has been reported to be a causative factor. The subsequent cytokine storm triggered by the immune response against SARS-CoV-2 infection has been reported to lead to symptoms being more severe. We herein report our experience with the onset of AAV following COVID-19 infection. We also report the course of anti-SARS-CoV-2 serum antibody titers following induction therapy, which suggests that vaccination and education concerning standard precautions are necessary in patients who require immunosuppressive therapy, even after COVID-19 infection.

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