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- Makiko Hayashi, Shinjiro Kaieda, Aya Kawaguchi, Masahiro Tsutsumi, Yumi Harada, Takuma Koga, Jun Akiba, Tomoaki Hoshino, and Hiroaki Ida.
- Department of Medicine, Division of Respirology, Neurology and Rheumatology, Kurume University School of Medicine, Japan.
- Intern. Med. 2021 Jan 1; 60 (23): 3823-3826.
AbstractWe herein report an unusual case of granulomatosis with polyangiitis (GPA) in a 65-year-old man in whom relapsed disease manifested as an anterior cheek nodule. Magnetic resonance imaging indicated the differential diagnoses of the subcutaneous nodule in the patient's anterior cheek to be inflammatory granulomatous lesions with GPA, malignancy, or infectious disease. A histopathological examination ruled out malignancy and infectious diseases, and necrotizing vasculitis was suspected. The subcutaneous nodule was successfully treated using rituximab, suggesting that it was associated with GPA, secondary to vasculitis. Clinicians should be aware of the possibility of such a rare manifestation of GPA.
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