• Leticia A Valdez-González, Araceli Méndez-Padrón, Rita A Gómez-Díaz, Adán Valladares-Salgado, Martha Catalina Sánchez-Becerra, Rafael Mondragón-González, Jaime Hernández-Rubí, Arturo González-Hermosillo, Miguel Cruz, Víctor Borja, and Niels H Wacher.
• a Unidad de Investigacion en Epidemiologia Clinica, UMAE Hospital de Especialidades, Centro Medico Siglo XXI. IMSS , Mexico City , Mexico.
• Scand. J. Clin. Lab. Invest. 2018 Feb 1; 78 (1-2): 87-93.

AbstractThe albumin-creatinine ratio is considered an indicator of microalbuminuria, precursor to chronic kidney disease, while HbA1c is used to measure glycemic control. Given the prevalence of diabetes-related nephropathy, spot testing of albumin has long been recommended as a preventative measure, for the timely detection of microalbuminuria. However, many countries do not have this testing available in primary care, and sometimes not even in second- and third-level care. The objective of this study was to compare agreement of the microalbuminuria and HbA1c results obtained in the laboratory with 'gold standard' techniques, with those obtained on site with a 'Point of Care' DCA Vantage™ device by Siemens. Results for the albumin-creatinine ratio and HbA1c from the Siemens DCA Vantage™ point of care device were compared with those from standard laboratory tests in 25 family medicine units in Mexico City and Toluca, State of Mexico, in patients diagnosed with type-2 diabetes. Agreement between the albumin values of the 2 tests was 0.745 (CI 95% 0.655-0.812). Agreement between the two measurement techniques for HbA1c was 0.970 (CI 95% 0.966-0.973). The results obtained were sufficiently comparative (Ri= 0.74 for albumin-creatinine ratio and Ri = 0.97 for HbA1c) to justify the use of the point of care device. Given the high agreement between the point of care device and laboratory tests, this device could be used to identify chronic kidney disease and glycemic control for more adequate treatment in patients with diabetes, especially in remote areas.

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