-
- N Attal.
- Inserm U-987, centre d'évaluation et de traitement de la douleur, CHU Ambroise-Paré, AP-HP, 92100 Boulogne-Billancourt, France; Université Versailles Saint-Quentin, 78035 Versailles, France. Electronic address: nadine.attal@aphp.fr.
- Rev Neurol France. 2019 Jan 1; 175 (1-2): 46-50.
AbstractWe provide an up-to-date review of the pharmacological treatment of neuropathic pain with emphasis on the latest evidence-based recommendations for its pharmacological treatment. Drugs proposed as first line include tricyclic antidepressants (particularly amitriptyline), serotonin-norepinephrine reuptake inhibitors (particularly duloxetine), pregabalin and gabapentin. Second line treatments include lidocaine plasters and capsaicin high concentration patches for peripheral neuropathic pain only, and tramadol. Third line treatments include strong opioids and botulinum toxin A (for peripheral neuropathic pain). Perspectives include the development of new compounds and a more personalized therapeutic approach, which is made possible by recent progress in the assessment and understanding of neuropathic pain.Copyright © 2018 Elsevier Masson SAS. All rights reserved.
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