• J. Trop. Pediatr. · Aug 2018

    Observational Study

    To Compare the Efficacy of Heated Humidified High-Flow Nasal Cannula and Continuous Positive Airway Pressure in Post-Extubation Period in VLBW Infants.

    • Bhawan Deep Garg, Naveen Bajaj, and Deepak Sharma.
    • Deep hospital, Ludhiana, Punjab, India.
    • J. Trop. Pediatr. 2018 Aug 1; 64 (4): 262-266.

    ObjectiveThe objective of this study was to compare efficacy of continuous positive airway pressure (CPAP) and heated humidified high-flow nasal cannula (HHHFNC) as noninvasive respiratory support in post-extubation period in very low birth weight (VLBW) infants.MethodThis retrospective study enrolled 136 neonates, ≤32 weeks gestation and ≤1500 grams birth weight, requiring noninvasive respiratory support during post-extubation period.ResultsThere was no significant difference in post-extubation failure in HHHFNC group when compared with CPAP group (p > 0.05) but post-extubation complication was significantly higher in CPAP group (p < 0.05) including nasal septal trauma and pneumothorax.ConclusionsIn neonates ≤32 weeks of gestational age, HHHFNC showed similar efficacy, and better safety profile than nasal-CPAP when used during post-extubation period for respiratory support.

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