• Giuseppina Frasca, Loredana Maggi, Luca Padua, Paola Emilia Ferrara, Giuseppe Granata, Ileana Minciotti, Emanuele Marzetti, Alessandro Specchia, Gianpaolo Ronconi, Alessia Rabini, Carlo Bertolini, and Diana Barbara Piazzini.
• Department of Physical Medicine and Rehabilitation, Catholic University, Rome, Italy. giuseppina.frasca@rm.unicatt.it
• Clin Rehabil. 2011 Dec 1; 25 (12): 1109-18.

ObjectiveTo determine the short-term effects of local microwave hyperthermia on pain and function in patients with mild to moderate idiopathic carpal tunnel syndrome.DesignDouble-blind randomized sham-controlled trial.SettingOutpatient clinic of the Department of Physical Medicine and Rehabilitation, University Hospital.ParticipantsTwenty-two patients with idiopathic carpal tunnel syndrome, 12 of whom had bilateral involvement, for a total of 34 wrists, divided into two groups: a hyperthermia active treatment group (number of wrists = 17) and a sham-controlled group (number of wrists = 17).InterventionSix sessions, two per week, of either hyperthermia or sham treatment were provided over a period of three weeks.Main MeasuresVisual analogue scale, Levine-Boston Self-Assessment Questionnaire (part I: evaluation of pain intensity; part II: evaluation of functional status) and neurophysiological assessments, were determined at baseline and at the end of the treatment.ResultsThe hyperthermia group experienced a significant improvement in pain (visual analogue scale: P = 0.002; Levine-Boston part I: P < 0.0001) and functional status (Levine-Boston part II: P = 0.002) relative to baseline. No improvements in pain intensity or functionality were observed in the sham-treated group. Changes in pain severity between baseline and the end of treatment were larger in the hyperthermia group than in the sham-controlled group (Δ visual analogue scale P = 0.004; Δ Levine-Boston part I: P = 0.009). No differences either intra or between groups were observed for median nerve conduction velocity.ConclusionHyperthermia provides short-term improvements in pain and function in patients with mild to moderate carpal tunnel syndrome.

17 keywords...

hide…