-
Comparative Study
[99mTc-MAG3 and 131I-OIH in patients with kidney insufficiency and with normal kidneys].
- U Keske, M Cordes, M Wilfling, J Hunger, N Hosten, and G Gahl.
- Abteilung für Innere Medizin mit Schwerpunkt Nephrologie, Universitätsklinikum Rudolf Virchow, Standort Charlottenburg, Berlin, West.
- Rofo. 1990 Mar 1; 152 (3): 287-92.
AbstractRenal clearance of 99mTc-mercaptoacetyltriglycine (MAG3) and 131J-orthoidohippurate (OIH) were compared by simultaneous measurement in 50 patients. Renal time-activity-curves of both radiopharmaceuticals were compared in 50 patients. With regard to the clearance, good correlation (r = 0.95) with a mean ratio MAG3-/OIH-clearance of 0.62 was found. No significant difference between patients with normal (n = 30) and impaired (n = 20) renal function could be demonstrated. Renal time activity curves and relative renal function showed good correspondence in patients with normal (n = 13) and impaired (n = 7) renal function. It is concluded that MAG3 may be used as substitute for OIH in patients with normal and impaired renal function.
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