• Ani Movsisyan, Jacob Burns, Renke Biallas, Michaela Coenen, Karin Geffert, Olaf Horstick, Irma Klerings, Lisa Maria Pfadenhauer, Peter von Philipsborn, Kerstin Sell, Brigitte Strahwald, Jan M Stratil, Stephan Voss, and Eva Rehfuess.
• Institute for Medical Information Processing, Biometry and Epidemiology, Ludwig Maximilians University Munich, Munich, Germany ani.movsisyan@ibe.med.uni-muenchen.de.
• BMJ Open. 2021 Apr 9; 11 (4): e041619.

ObjectivesTo comprehensively map the existing evidence assessing the impact of travel-related control measures for containment of the SARS-CoV-2/COVID-19 pandemic.DesignRapid evidence map.Data SourcesMEDLINE, Embase and Web of Science, and COVID-19 specific databases offered by the US Centers for Disease Control and Prevention and the WHO.Eligibility CriteriaWe included studies in human populations susceptible to SARS-CoV-2/COVID-19, SARS-CoV-1/severe acute respiratory syndrome, Middle East respiratory syndrome coronavirus/Middle East respiratory syndrome or influenza. Interventions of interest were travel-related control measures affecting travel across national or subnational borders. Outcomes of interest included infectious disease, screening, other health, economic and social outcomes. We considered all empirical studies that quantitatively evaluate impact available in Armenian, English, French, German, Italian and Russian based on the team's language capacities.Data Extraction And SynthesisWe extracted data from included studies in a standardised manner and mapped them to a priori and (one) post hoc defined categories.ResultsWe included 122 studies assessing travel-related control measures. These studies were undertaken across the globe, most in the Western Pacific region (n=71). A large proportion of studies focused on COVID-19 (n=59), but a number of studies also examined SARS, MERS and influenza. We identified studies on border closures (n=3), entry/exit screening (n=31), travel-related quarantine (n=6), travel bans (n=8) and travel restrictions (n=25). Many addressed a bundle of travel-related control measures (n=49). Most studies assessed infectious disease (n=98) and/or screening-related (n=25) outcomes; we found only limited evidence on economic and social outcomes. Studies applied numerous methods, both inferential and descriptive in nature, ranging from simple observational methods to complex modelling techniques.ConclusionsWe identified a heterogeneous and complex evidence base on travel-related control measures. While this map is not sufficient to assess the effectiveness of different measures, it outlines aspects regarding interventions and outcomes, as well as study methodology and reporting that could inform future research and evidence synthesis.© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.

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