• S Karande and R Venkataraman.
• Department of Pediatrics, Division of Pediatric Neurology, Learning Disability Clinic, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, Maharashtra, India.
• J Postgrad Med. 2012 Oct 1; 58 (4): 246-54.

BackgroundSpecific learning disability (SpLD) often remains undetected, resulting in the afflicted child experiencing chronic poor school performance.AimsTo measure and analyze the self-perceived health-related quality of life (HRQoL) of children with newly-diagnosed SpLD.Settings And DesignCross-sectional questionnaire-based study in our clinic.Materials And MethodsFrom February to December 2008, 150 children consecutively diagnosed as having SpLD were enrolled and their HRQoL documented using the DISABKIDS chronic generic module self-report version instrument.Statistical AnalysisMultiple regression analysis was carried out for determining the 'independent' impact that each of the clinical and socio-demographic variables had on a poor facet score outcome and on a poor total score outcome.ResultsClinically significant deficits were detected in all 6 facets, namely: 'large deficits (effect size ≥-0.8)' in "social exclusion", "emotion", "limitation", "treatment", and "independence"; and 'medium deficit (effect size -0.5 to <-0.8)' in "social inclusion"; and 'large deficit' in "total score". Multivariate analysis revealed that: (i) not belonging to the upper socio-economic strata of society was an independent predictor of a poor "independence" facet outcome (P=0.010, OR=1.99, 95% CI: 1.18 to 3.37); (ii) not having experienced class detainment was an independent predictor of a poor "emotion" facet outcome (P=0.008, OR=3.04, 95% CI: 1.34 to 6.85); (iii) first-born status was an independent predictor of a poor "limitation" facet outcome (P=0.022, OR=2.60, 95% CI: 1.15 to 5.90); and (iv) female gender was an independent predictor of a poor "social exclusion" facet outcome (P=0.024, OR=0.28, 95% CI: 0.09 to 0.85) and a poor "overall health" outcome (P=0.025, OR=0.32, 95% CI: 0.12 to 0.87).ConclusionsChildren with newly-diagnosed SpLD perceive their psychosocial, physical, and overall HRQoL to be significantly compromised.

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