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Acta médica portuguesa · Jul 1995
Review[Ret proto-oncogene mutations associated with type 2 multiple endocrine neoplasms (MEN 2). Clinical implications].
- M J Bugalho and L G Sobrinho.
- Serviço de Endocrinologia, Instituto Português de Oncologia Francisco Gentil, Lisboa.
- Acta Med Port. 1995 Jul 1; 8 (7-8): 419-24.
AbstractMultiple endocrine neoplasia type 2 (MEN 2) is an autosomal dominant cancer syndrome. Clinical features and diagnostic aspects of this syndrome are reviewed with a focus on progress biochemical screening to genetic analysis of those at risk. The clinical implications resulting from the application of the new methods of molecular biology are discussed.
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