Genomics in primary care practice.

Primary care · Jun 2014

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Genomics in primary care practice.

This article discusses the clinical utility of genomic information for personalized preventive care of a healthy adult. Family health history is currently the most applicable genomic predictor for common, multifactorial diseases, and can also show patterns that suggest an inherited high susceptibility to a particular form of cancer or other disease. ⋯ DNA and family history analyses give information that is probabilistic, not deterministic. Therefore, family history can highlight behavioral, social, or cultural risk factors that can be modified to prevent diseases.

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- Kathryn Teng and Louise S Acheson.
- Internal Medicine, Center for Personalized Healthcare (Cleveland Clinic), 9500 Euclid Avenue, NE5-203, Cleveland, OH 44195, USA. Electronic address: tengk@ccf.org.
- Prim. Care. 2014 Jun 1; 41 (2): 421-35.
AbstractThis article discusses the clinical utility of genomic information for personalized preventive care of a healthy adult. Family health history is currently the most applicable genomic predictor for common, multifactorial diseases, and can also show patterns that suggest an inherited high susceptibility to a particular form of cancer or other disease. Both bloodline ancestry and shared environmental factors are important predictors for many disease states. DNA and family history analyses give information that is probabilistic, not deterministic. Therefore, family history can highlight behavioral, social, or cultural risk factors that can be modified to prevent diseases. Copyright © 2014 Elsevier Inc. All rights reserved.

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Genomics in primary care practice.

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