• Cheryl Ritenbaugh, Richard Hammerschlag, Carlo Calabrese, Scott Mist, Mikel Aickin, Elizabeth Sutherland, Joseph Leben, Lynn Debar, Charles Elder, and Samuel F Dworkin.
• Department of Family and Community Medicine, The University of Arizona, Tucson, AZ 85719, USA. ritenbau@email.arizona.edu
• J Altern Complement Med. 2008 Jun 1;14(5):475-87.

ObjectivesTo assess the feasibility and acceptability of studying whole systems of Traditional Chinese Medicine (TCM) and Naturopathic medicine (NM) in the treatment of temporomandibular disorders (TMD), and to determine whether there is indication to support further research.DesignA pilot study using a randomized controlled clinical trial design of whole system TCM and NM versus state-of-the-art specialty care (SC).Setting/LocationKaiser Permanente Northwest (KPNW), and practitioner offices in Portland, Oregon.SubjectsOne hundred and sixty (160) women 25-55 years of age attending a KPNW TMD specialty clinic.InterventionsWhole system TCM and NM, and KPNW TMD clinic SC; the intervention protocols were designed to model the individually tailored type of community care offered in alternative medicine practices in Portland and in the KPNW TMD clinic, using protocols that enhanced similarities among practitioners within each system and permitted full descriptions of the treatments provided.Outcome MeasuresTMD was ascertained using the Research Diagnostic Criteria/TMD; outcomes were self-reported worst and average facial pain and interference with activities (scaled 0-10 where 10 is worst).ResultsOf 948 consecutive eligible patients, 160 were randomized to one of three arms; 128 provided endpoint data. TCM and NM demonstrated significantly greater in-treatment reductions for worst facial pain compared to SC (adjusted regression analysis; higher negative values indicate greater improvement, = -1.11 +/- 0.43, p = 0.010 and -1.02 +/- 0.45, p = 0.025 for TCM and NM, respectively, compared to SC) and at 3 months post-treatment (-1.07 +/- 0.51, p = 0.037 and -1.27 +/- 0.54, p = 0.019 for TCM and NM versus SC, respectively). Additionally, TCM provided significantly greater decreases in average pain than SC; NM provided significantly greater decreases than SC or TCM in TMD-related psychosocial interference.ConclusionsThese alternative medicine approaches each resulted in significantly greater reduction of pain and psychosocial interference than SC. Further research on the potential benefits of traditional whole systems of medicine for TMD appears warranted.

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