• J. Investig. Med. · Oct 2012

    Review

    Translational research and the evolving landscape for biomedical innovation.

    • Kenneth I Kaitin.
    • Tufts Center for the Study of Drug Development, Tufts University School of Medicine, Tufts University, Boston, MA 02111, USA. kenneth.kaitin@tufts.edu
    • J. Investig. Med. 2012 Oct 1; 60 (7): 995-8.

    AbstractThis article addresses current challenges facing pharmaceutical and biopharmaceutical developers, including the expiration of patents on many high-revenue-generating products, increasing competition in the marketplace, low public support, high regulatory hurdles, and the increasing time, cost, and risk of new product development. To meet these challenges, drug developers are looking to new models of innovation to improve efficiency, lower risk, and increase output. These new models include codevelopment agreements with small companies, multicompany consortia, and strategic partnerships with academic research centers. In the United States and the European Union, the government is supporting these efforts by creating incentives for academic centers to foster translational research and become more "commercially minded". The goal for all stakeholders is to reduce the barriers to product development and bring new medicines to market in a timely and cost-efficient manner.

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