• Terapevt Arkh · Jan 2001

    Comparative Study

    [Features of microcirculatory disorders in acute and recurrent hemorrhagic vasculitis (Schönlein-Henoch disease)].

    • O A Nazarova, V A Bobkov, S V Ionova, and T V Drozdova.
    • Terapevt Arkh. 2001 Jan 1; 73 (5): 39-43.

    AimTo study microcirculatory disturbances in acute and chronic hemorrhagic vasculitis (HV).Material And MethodsThe examination of 44 HV patients included clinical and immunological examinations, conjunctival biomicroscopy, tests for blood viscosity, aggregation of erythrocytes, coagulation parameters. In 8 patients morphological examination of skin microvessels was made (light microscopy and electron microscopy).ResultsChanges in microcirculation of patients with acute HV were characterized by increased IgA and red cell aggregation, tendency to hypercoagulation. Morphologically, there was high permeability of the microvessels wall. In patients with chronic HV laboratory parameters normalized except elevated level of circulating immune complexes and red cell aggregation. Morphological picture of microcirculatory disturbances in patients with chronic HV was characterized by productive vasculitis.ConclusionIn HV patients microcirculatory disorders caused by immunologic mechanisms are realized through increased permeability of microvessel wall, high aggregation of erythrocytes in microvessels and hypercoagulation in acute HV. In patients with chronic HV productive vasculitis and high aggregation of erythrocytes are registered.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…