• P Brian Volpp, Khanh Han, A Robert Kagan, and Michael Tome.
• Department of Radiation Oncology, Kaiser Permanente, Los Angeles, CA 90027, USA. pvolpp@yahoo.com
• Int. J. Radiat. Oncol. Biol. Phys. 2007 Nov 15; 69 (4): 1199-204.

PurposeSpinal cord ependymomas are rare tumors, accounting for <2% of all primary central nervous system tumors. This study assessed the treatment outcomes for patients diagnosed with spinal cord ependymomas within the Southern California Kaiser Permanente system.Methods And MaterialsWe studied 23 patients treated with surgery with or without external beam radiotherapy (EBRT). The local and distant control rates and overall survival rates were determined.ResultsThe overall local control, overall recurrence, and 9-year overall survival rate was 96%, 17.4%, and 63.9%, respectively.ConclusionsThe results of our study indicate that en bloc gross total resection should be the initial treatment, with radiotherapy reserved primarily for postoperative cases with unfavorable characteristics such as residual tumor, anaplastic histologic features, or piecemeal resection. Excellent local control and overall survival rates can be achieved using modern microsurgical techniques, with or without local radiotherapy.

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