• Medicina clinica · Dec 2016

    Review

    Fibrous dysplasia. Clinical review and therapeutic management.

    • Helena Florez, Pilar Peris, and Núria Guañabens.
    • Servicio de Reumatología, Hospital Clínic, Universidad de Barcelona, Barcelona, España.
    • Med Clin (Barc). 2016 Dec 16; 147 (12): 547-553.

    AbstractFibrous dysplasia is a skeletal disorder that is associated with a wide spectrum of clinical manifestations, including localized asymptomatic forms and extensive severe forms with severe bone deformities and endocrinological alterations, depending on age, location, extent and associated processes. Although the treatment of choice is based on bisphosphonates, the therapeutic efficacy of these agents in the control of disease activity remains uncertain. This article reviews the current data available on the treatment of this disease as well as the preliminary data on new therapeutic approaches.Copyright © 2016 Elsevier España, S.L.U. All rights reserved.

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