• J. Korean Med. Sci. · Nov 2021

    Trend of Antibiotic Use in Children with Acute Otitis Media in Korea.

    • Kyu Hyun Park, Seung-Ah Choe, Ju-Young Shin, and Young June Choe.
    • Department of Pediatrics, Korea University Anam Hospital, Seoul, Korea.
    • J. Korean Med. Sci. 2021 Nov 29; 36 (46): e317.

    AbstractPublic interventions have shown to optimize the use of antibiotics in children with acute otitis media (AOM). In this study, we describe the AOM-related antibiotic use among children in South Korea using national cohort data. We retrieved the Health Insurance Review & Assessment Service data to construct a national cohort of children aged 0-6 years who had been diagnosed with AOM between 2012 and 2018. Of 25,212,264 children included, the antibiotic prescription has increased for amoxicillin/amoxicillin-clavulanate from 56.1% in 2012 to 61.8% in 2018. Prescription has decreased for cephalosporin (35.1% in 2012 to 31.8% in 2018) and macrolide (8.7% in 2012 to 6.4% in 2018). National cohort data have shown an increased trend in AOM-related aminopenicillin prescription and downward trend cephalosporin and macrolide use in South Korea. A multi-faceted approach is required to control the antimicrobial resistance at a population level.© 2021 The Korean Academy of Medical Sciences.

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