• J Calleja Kempin, G Clemente Ricote, J Pérez Ferreiroa, R Bañares Cañizares, J R Polo Melero, J L García Sabrido, E Valdecantos Montes, L Olmedilla, L Santos, and J Pérez Peña.
• Cirugía General y Aparato Digestivo, Hospital General Universitario Giregorio Marañón.
• Rev Clin Esp. 1995 Apr 1; 195 (4): 207-13.

AbstractDuring a 3-year period between 1990 and 1993, 100 patients received orthotopic liver transplantation at the "Gregorio Marañón" University General Hospital. The mean age of the patients was relatively high (46.9 +/- 10 years), with an important number of cirrhotic patients (91%). The rate of primary liver failure was relatively low (4.5% of transplantations) although 12 cases with more than 55 years were included in the present series. Eleven retransplantations were performed, 8 for early failure of the graft and 3 for chronic failure. Postoperative complications of the graft were vascular in 9 cases, biliary in 17 cases, and acute rejection (cellular) in 70 patients, although only 50 of these patients required treatment with steroid boluses. Infections were diagnosed in 60 cases with 80% of major infections, 6 of them caused by Aspergillus fumigatus that were lethal in all the cases. Postoperative survival was 82%, 72%, 69% and 69% at 1 month, 6 months, 1 year and 2 years respectively.

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