• American family physician · Aug 2001

    Review

    Evaluating the child with purpura.

    • A K Leung and K W Chan.
    • University of Calgary, Faculty of Medicine, Alberta, Canada.
    • Am Fam Physician. 2001 Aug 1; 64 (3): 419-28.

    AbstractPurpura is the result of hemorrhage into the skin or mucosal membrane. It may represent a relatively benign condition or herald the presence of a serious underlying disorder. Purpura may be secondary to thrombocytopenia, platelet dysfunction, coagulation factor deficiency or vascular defect. Investigation to confirm a diagnosis or to seek reassurance is important. Frequently, the diagnosis can be established on the basis of a careful history and physical examination, and a few key laboratory tests. Indicated tests include a complete blood cell count with platelet count, a peripheral blood smear, and prothrombin and activated partial thromboplastin times.

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