• American family physician · Dec 2005

    Review

    St. John's wort.

    • Silvana Lawvere and Martin C Mahoney.
    • Department of Clinical Prevention, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.
    • Am Fam Physician. 2005 Dec 1; 72 (11): 2249-54.

    AbstractSt. John's wort has been used to treat a variety of conditions. Several brands are standardized for content of hypericin and hyperforin, which are among the most researched active components of St. John's wort. St. John's wort has been found to be superior to placebo and equivalent to standard antidepressants for the treatment of mild to moderate depression. Studies of St. John's wort for the treatment of major depression have had conflicting results. St. John's wort is generally well tolerated, although it may potentially reduce the effectiveness of several pharmaceutical drugs.

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