• Presse Med · Dec 2005

    Case Reports

    [Spontaneous splenic hematoma: trauma injury or drug reaction or both?].

    • J-C Chakarian, F Héron, C Belizna, F Hervé, J-H Maillochaud, I Marie, and H Lévesque.
    • Département de médecine interne, CHU Rouen-Boisguillaume, Rouen (76).
    • Presse Med. 2005 Dec 17; 34 (22 Pt 1): 171717181717-8.

    IntroductionSpontaneous splenic hematomas are uncommon and frequently associated with infectious, hematologic, or neoplastic diseases. Presentation is typically acute but progressive forms have been described.CaseWe report the case of a 45-year-old man consulting for abdominal pain that was found to be due to a spontaneous splenic hematoma. No recent injuries, infections, or hematologic, neoplastic or gastrointestinal diseases were found, but the patient had had a minor injury 9 months earlier and had been treated with selective serotonin reuptake inhibitors (venlafaxine) for the past year. This history suggested that the drug might play a role.DiscussionAlthough the likely cause of this splenic hematoma appears to be a minor injury 9 months before the onset of pain, we cannot rule out the possibility that selective serotonin reuptake inhibitor treatment was a predisposing factor.

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