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Southern medical journal · May 2011
Case ReportsTumor-induced osteomalacia (TIO): atypical presentation.
- Waseem Khaliq, Praveen Cheripalli, and Krishnarao Tangella.
- Johns Hopkins University School of Medicine, Department of Medicine, Baltimore, MD, USA. khaliqmd@gmail.com
- South. Med. J. 2011 May 1; 104 (5): 348-50.
AbstractTumor-induced osteomalacia is a rare acquired condition characterized by phosphaturia, hypophosphatemia and osteomalacia. We report an unusual presentation in a 15-year-old healthy male with a two-week history of cough and chest pain. The chest radiograph showed right middle lobe opacity and chest CT revealed a mass in the extra pleural space. A biopsy showed chondro-myxoidstroma with osteoid formation. Diagnosis was confirmed with the above findings and hypophosphatemia. The patient's symptoms resolved after complete surgical excision of the mass. Tumor-induced osteomalacia, although a rare disorder, can be a diagnostic challenge, especially in patients presenting with atypical symptoms.
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