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- Kayla Cox, Brandon Alford, and Hatem Soliman.
- From the Lake Erie College of Osteopathic Medicine, Bradenton, Florida, the University of South Florida College of Medicine, Tampa, and the H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
- South. Med. J. 2017 Oct 1; 110 (10): 632-637.
AbstractThe field of medical oncology is experiencing a period of rapid evolution owing to advances in the fields of genomics, tumor biology, and immunology. These disciplines have provided valuable insights into the heterogeneity between breast tumors, key oncogenic drivers, and the role of the immune system in the natural history of breast cancer. This knowledge is translating into many novel therapeutic strategies using personalized medicines, targeted drug delivery systems, and immunomodulatory agents in the treatment of both the early and metastatic stages of the disease. This review article attempts to cover the major developments in experimental therapeutics and how they relate to our understanding of breast cancer and its various biologic subtypes.
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