• Eur J Anaesthesiol · Jul 1997

    Randomized Controlled Trial Clinical Trial

    Antiseptic-impregnated central venous catheters reduce the incidence of bacterial colonization and associated infection in immunocompromised transplant patients.

    • S J George, P Vuddamalay, and M J Boscoe.
    • Department of Anaesthesia, St George's Hospital, London, UK.
    • Eur J Anaesthesiol. 1997 Jul 1; 14 (4): 428-31.

    AbstractThe incidence of bacterial colonization of central venous catheters using a standard polyurethane catheter was compared with that using an antiseptic (silver sulphadiazine and chlorhexidine) impregnated catheter in a group of patients with thoracic organ transplantation. Colonization was reduced from 25 of 35 standard catheters to 10 of 44 study catheters (P < 0.002), a 68% reduction. Similarly, the incidence of concomitant infection, by the same organism at another site was reduced from 10 of 35 standard catheters to 4 of 44 study catheters (P < 0.03), a 63% reduction.

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