• Clinics · Jan 2014

    Review

    New immunosuppressive agents in pediatric transplantation.

    • Christina Nguyen and Ron Shapiro.
    • Division of Pediatric Nephrology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, United States.
    • Clinics (Sao Paulo). 2014 Jan 1; 69 Suppl 1: 8-16.

    AbstractImmunosuppressive therapy in pediatrics continues to evolve. Over the past decade, newer immunosuppressive agents have been introduced into adult and pediatric transplant patients with the goal of improving patient and allograft survival. Unfortunately, large-scale randomized clinical trials are not commonly performed in children. The purpose of this review is to discuss the newer immunosuppressive agents available for induction therapy, maintenance immunosuppression, and the treatment of rejection.

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